Electrical Properties of Chlorpromazine

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Abstract
Chlorpromazine (10‐dimethylaminopropyl phenothiazine) in the form of slabs cast from the melt is a semiconductor. The activation energy of conductivity has an average value of E=2.1 ev, referring to the equation σ=σ0 exp(—E/2kT), above a transition temperature of 32°C. There is no significant change of E upon fusion, its value remaining constant up to 80°C. The transition has been confirmed by thermal analysis,dielectricmeasurements, and by infrared spectroscopy. The spectra indicate that the side chain as well as the ring system are affected by the transition, which is believed to be due to an unfolding of the sidechain above a critical temperature, this causing a change in the micellar association of the substance. Values are reported, as functions of temperature, for the refractive index, the permittivity at 1 Mc/sec and at 1592 cps, the parallel ac conductivity and the loss tangent at the latter, lower, frequency. The substance is diamagnetic.