Concentration of Luteinizing and Follicle-Stimulating Hormones in Peripheral and Ovarian Venous Plasma1
- 1 August 1969
- journal article
- other
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 29 (8) , 1083-1089
- https://doi.org/10.1210/jcem-29-8-1083
Abstract
LH and FSH were measured by radioimmunoassay in peripheral and ovarian venous plasmas of 27 women at different times during the menstrual cycle and in 25 women treated with various antifertility compounds. The concentration of LH in peripheral vein was greater than that in the ovarian vein by 4.75 mIU/ml±1.2 (se) in the follicular phase (p .001) and 6.2 mIU/ml + 0.56 (se) in the luteal phase (p <.001). There was no statistically significant difference between the concentrations of FSH in peripheral and ovarian venous plasmas. Twenty-five women had been treated with 1 of 4 gestagen or gestagen-estrogen preparations. They were all anovulatory. There was no difference between concentrations of either LH or FSH in peripheral and ovarian venous plasmas. LH appears to be metabolized by the ovary during a normal menstrual cycle but not by the ovary in which ovulation is blocked by chemical contraceptives.Keywords
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