Novel C-Terminus Modifications of the Dmt-Tic Motif: A New Class of Dipeptide Analogues Showing Altered Pharmacological Profiles Toward the Opioid Receptors
- 16 June 2001
- journal article
- letter
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 44 (15) , 2387-2390
- https://doi.org/10.1021/jm015532k
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Further Studies on the Dmt-Tic Pharmacophore: Hydrophobic Substituents at the C-Terminus Endow δ Antagonists To Manifest μ Agonism or μ AntagonismJournal of Medicinal Chemistry, 1999
- Design of δ-opioid peptide antagonists for emerging drug applicationsDrug Discovery Today, 1998
- The receptor‐bound conformation of H‐Tyr‐Tic‐(Phe‐Phe)‐OH‐related δ‐opioid antagonists contains all trans peptide bondsChemical Biology & Drug Design, 1998
- New δ-opioid antagonists as pharmacological probesTrends in Pharmacological Sciences, 1998
- The stereochemical requirements of the novel δ-opioid selective dipeptide antagonist TMT-TicBioorganic & Medicinal Chemistry Letters, 1997
- Comparative analysis of various proposed models of the receptor-bound conformation of H-tyr-Tic-Phe OH related ?-opioid antagonistsBiopolymers, 1995
- Theoretical conformational analysis of the opioid δ antagonist H‐Tyr‐Tic‐Phe‐OH and the μ agonist H‐Tyr‐D‐Tic‐Phe‐NH2Biopolymers, 1994
- Newly discovered stereochemical requirements in the side-chain conformation of .delta. opioid agonists for recognizing opioid .delta. receptorsJournal of Medicinal Chemistry, 1994
- Selective Opioid DipeptidesBiochemical and Biophysical Research Communications, 1994
- TIPP[.psi.]: a highly potent and stable pseudopeptide .delta. opioid receptor antagonist with extraordinary .delta. selectivityJournal of Medicinal Chemistry, 1993