Glutamine- and Asparagine-Dependent Protein Synthesis in Maturing Legume Cotyledons Culturedin vitro

Abstract
Legume cotyledons have been grown in sterile culture and shown to synthesize up to 16 mg protein in 5 d when supplied with either asparagine or glutamine as sole nitrogen sources. Glutamate, nitrate, and ureides also served as nitrogen sources for protein synthesis but to a lesser extent. Methionine sulphoximine and azaserine inhibited asparagine-dependent protein synthesis suggesting that ammonia is liberated from asparagine which is reassimilated via glutamine synthetase and glutamate synthase.