Paroxysmal dysarthria and ataxia in multiple sclerosis

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Abstract
Paroxysmal dysarthria and ataxia in 2 patients with multiple sclerosis are reported. These occurred in brief attacks lasting 10-20 sec. with sudden onset and cessation, and recurred over a period of months, eventually disappearing completely. The various forms of disturbance of speech described in multiple sclerosis are reviewed. A search of the literature has failed to reveal any similar cases of paroxysmal dysarthria. The differential diagnosis is discussed and, for the reasons presented, it is suggested that the attacks may originate in a disturbance situated in the cerebellum or in its connections in the brain stem. The implication of these attacks in the pathogenesis of multiple sclerosis is briefly discussed.

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