Sodium Cyanoborohydride Reduction of (Benzyloxycarbonyl)- and (tert-Butoxycarbonyl)hydrazones
- 1 January 1991
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1991 (07) , 536-539
- https://doi.org/10.1055/s-1991-26511
Abstract
(Benzyloxycarbonyl)- and (tert-butoxycarbonyl)hydrazones are easily reduced by sodium cyanoborohydride in acidic medium. The method is an alternative to catalytic hydrogenation and allows ready access to both N-benzyloxycarbonyl and N-tert-butoxycarbonyl protected N′ -alkyl- and N′-arylmethylhydrazines. The products can be isolated as the solid, stable cyanoborane adducts.Keywords
This publication has 0 references indexed in Scilit: