Cytochrome a 3 Structure in Carbon Monoxide-Bound Cytochrome Oxidase
- 20 July 1984
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 225 (4659) , 329-331
- https://doi.org/10.1126/science.6330890
Abstract
The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.Keywords
This publication has 22 references indexed in Scilit:
- Resonance Raman detection of iron-carbonmonoxy stretching and iron-carbon-oxygen bending vibrations in sterically hindered carbonmonoxy "strapped hemes". A structural probe of iron-carbon-oxygen distortionBiochemistry, 1983
- Resonance Raman studies of carbon monoxide binding to iron "picket fence" porphyrin with unhindered and hindered axial bases. An inverse relationship between binding affinity and the strength of iron-carbon bondBiochemistry, 1983
- The nature of ferrous haem protein complexes prepared by photolysisBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982
- Resonance Raman investigation of carbon monoxide bonding in (carbon monoxy)hemoglobin and -myoglobin: detection of iron-carbon monoxide stretching and iron-carbon-oxygen bending vibrations and influence of the quaternary structure changeBiochemistry, 1982
- Coordination geometries and vibrational properties of cytochromes a and a3 in cytochrome oxidase from soret excitation Raman spectroscopyBiochemistry, 1981
- Raman difference spectroscopy as a probe of biological moleculesJournal of Raman Spectroscopy, 1981
- Cytochrome c oxidase Structure and catalytic activityBiochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1979
- Resonance Raman spectra and optical properties of oxidized cytochrome oxidaseBiochemistry, 1979
- The Binding of Carbon Monoxide to Cytochrome c OxidaseEuropean Journal of Biochemistry, 1977
- Quantitative infrared spectroscopy of co complexes of cytochrome c oxidase, hemoglobin and myoglobin: Evidence for one co per hemeBiochemical and Biophysical Research Communications, 1975