Mevalonolactone inhibits the rate of synthesis and enhances the rate of degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat hepatocytes.
Open Access
- 1 June 1983
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 258 (12) , 7272-7275
- https://doi.org/10.1016/s0021-9258(18)32171-9
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA.Proceedings of the National Academy of Sciences, 1982
- Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells.Proceedings of the National Academy of Sciences, 1982
- Proteinase involvement in the solubilization of 3-hydroxy-3-methylglutaryl coenzyme a reductaseBiochemical and Biophysical Research Communications, 1981
- In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone.Proceedings of the National Academy of Sciences, 1980
- Studies on the mechanisms of the rapid modulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in intact liver by mevalonolactone and 25-hydroxycholesterolBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1980
- A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gelsAnalytical Biochemistry, 1980
- Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylateAnalytical Biochemistry, 1979
- Biological Activity of Some Oxygenated SterolsScience, 1978
- [18] Methods for analysis of enzyme synthesis and degradation in animal tissuesPublished by Elsevier ,1975
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970