Malate dehydrogenase: viability of cytosolic nulls and lethality of mitochondrial nulls in maize.
Open Access
- 1 March 1981
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (3) , 1783-1785
- https://doi.org/10.1073/pnas.78.3.1783
Abstract
Five independently inherited loci on five distinct chromosomes encode the mitochondrial and cytosolic isozymes of NAD-dependent malate dehydrogenase (MDH; L-malate:NAD+ oxidoreductase, EC 1.1.1.37). Multiple alleles, including electrophoretic nulls, occur for each locus. However, a single allele of normal activity at one of the three loci encoding the mitochondrial MDHs is sufficient for normal development, whereas plants with essentially no cytosolic MDH activity function normally. The requirement of a normal activity allele at one of the three structural loci encoding the mitochondrial MDHs demonstrates in plants that a commonly studied dehydrogenase enzyme is essential for normal embryogenesis.This publication has 5 references indexed in Scilit:
- Duplicated cytosolic malate dehydrogenase genes in Zea maysProceedings of the National Academy of Sciences, 1980
- GENETIC BASIS OF THE MAJOR MALATE DEHYDROGENASE ISOZYMES IN MAIZEGenetics, 1980
- Enzyme null alleles in natural populations of Drosophila melanogaster : Frequencies in a North Carolina populationProceedings of the National Academy of Sciences, 1980