Caspofungin Susceptibility Testing of Candida inconspicua : Correlation of Different Methods with the Minimal Fungicidal Concentration
- 1 August 2005
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (8) , 3486-3488
- https://doi.org/10.1128/aac.49.8.3486-3488.2005
Abstract
Minimal inhibitory and minimal fungicidal concentrations of caspofungin were determined for 48 Candida inconspicua isolates. By using CLSI (formerly NCCLS) methodology with the partial inhibition endpoint criterion, caspofungin exhibited a good fungicidal effect against C. inconspicua (the MIC 90 was 0.25 μg/ml and the minimum fungicidal concentration [MFC] was 0.5 μg/ml after 24 h). Total inhibition yielded falsely elevated MICs, exceeding even the respective MFCs.Keywords
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