Valproic acid down‐regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase‐1 and ‐2 in rat brain
Open Access
- 28 March 2003
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 85 (3) , 690-696
- https://doi.org/10.1046/j.1471-4159.2003.01701.x
Abstract
Sodium valproate, a mood stabilizer, when chronically administered to rats (200 mg/kg i.p. daily for 30 days) significantly reduced the brain protein levels of cyclooxygenase (COX)‐1 and COX‐2, witho...Keywords
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