Moduretic-induced metabolic acidosis and hyperkalaemia
Open Access
- 1 May 1980
- journal article
- case report
- Published by Oxford University Press (OUP)
- Vol. 56 (655) , 348-350
- https://doi.org/10.1136/pgmj.56.655.348
Abstract
Summary: A patient who developed significant metabolic acidosis and severe hyperkalaemia while taking Moduretic (amiloride and hydrochlorothiazide) is reported. During the period of hyperkalaemia (maximum potassium 7-6 mmol/l) the patient’s whole body potassium content was normal. His acid-base balance and serum potassium returned to normal some 10 days after stopping the drug. The possible mechanism of acidosis and hyperkalaemia in this patient is discussed.Keywords
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