THE EOSINOPHIL RESPONSE TO STRESS OF PATIENTS WITH SURGICALLY PRODUCED THALAMIC AND HYPOTHALAMIC LESIONS*†

Publisher Website
Google Scholar
Abstract
Four of 15 schizophrenic patients showed changes in the eosinophil response to ACTH, insulin and epinephrine following production of thalamic and hypothalamic lesions by the Spiegel-Wycis apparatus. Lesions in these 4 patients involved the anterior and dorso-medial nuclei of the thalamus and the posterolateral portion of the hypothalamus. Abnormalities appeared 4 weeks post-operatively; they were greatest when the test material was epinephrine, and least when it was ACTH. Three of the 4 patients showed no change in insulin sensitivity. The 4th showed insulin hypersensitivity and possibly hypoglycemic unresponsiveness. This same patient also displayed a sustained rise in the fasting eosinophil level following a 2d operation.

This publication has 1 reference indexed in Scilit: