A Simple Route to β,β-Trehalose via Trichloroacetimidates
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 3 (2) , 343-348
- https://doi.org/10.1080/07328308408058825
Abstract
The reaction of 2,3,4,6-tetra-O-acetyl-β-D-glucopyranose with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl trichloroacetimidate in CH2Cl2 promoted by BF3;OEt2 gives β,β-octaacetyltrehalose in up to 58% isolated yield, which is readily deacetylated to β,β-trehalose. The corresponding 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl penta-fluorophenylimidate is configurationally stable and inert to coupling under mild conditions.This publication has 5 references indexed in Scilit:
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