AUTORADIOGRAPHIC STUDY OF RETROCORNEAL MEMBRANES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 10  (11) , 1547-1552
Abstract
Fibrous membranes in the posterior cornea occur in failed transplants. The role of corneal endothelium in the formation of these membranes was investigated. The corneal cellular components of rabbit corneas were labeled with tritiated thymidine. Labeled rabbit corneal stroma was replaced with unlabeled tissue (pre-Descemet''s lamellar graft), leaving only labeled endothelium. Weeks later small unlabeled penetrating grafts, without endothelium, were placed inside this lamellar graft. The surrounding labeled host endothelial cells were found in a fine retrograft membrane and in the scar of grafts. The experiment demonstrated that host endothelial cells participate in the formation of retrograft membranes, but it does not exclude other origin of fibroblasts.

This publication has 0 references indexed in Scilit: