Pituitary metastasis

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Abstract
Symptomatic pituitary metastases are uncommon and may be difficult to differentiate from pituitary adenomas. To ascertain the incidence of pituitary tumors in cancer patients and to characterize the clinical presentation of pituitary metastases, clinical studies of these tumors during 1976-1979 and a recent series of 500 consecutive autopsy examinations of the pituitary fossa and gland were reviewed. In the clinical series a histologic diagnosis was made in 3 of 5 patients. Radiologic evaluation, including polytomography and computed tomography, did not reliably distinguish metastasis from adenoma, but the clinical syndromes were distinctive. In the autopsy series pituitary metastases were found in 3.6% of cases, pituitary adenomas in 1.8%.

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