Convenient Synthesis of Benzoylecgonine Ethyl Ester, a Homolog of Cocaine
- 1 April 1992
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 22 (7) , 1027-1032
- https://doi.org/10.1080/00397919208019293
Abstract
Benzoylecgonine reacted with tetramethylethylenediamine to form a lipophilic ion pair, which was alkylated in the absence of water. The ethyl ester was readily recrystallized for pharmacological studies.Keywords
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