Aureomycin in the Prophylaxis of Rheumatic Fever

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Abstract
DESPITE recent progress, the prevention of rheumatic fever remains a challenging problem. The investigation of this subject is made difficult by the lack of basic knowledge concerning the disease itself.1 Rheumatic fever is widely recognized as a frequent and potentially serious condition; yet its actual incidence cannot be accurately determined.2 Frequently, the clinical picture is quite atypical: there may be no arthritis or arthralgia; and the disease may be extremely severe or very mild. No precise diagnostic procedure is available.3 Doubtless, therefore, numerous cases are overlooked and misdiagnosed. Even so, it is estimated that 200,000 to 250,000 persons in the . . .