Benzacridines VI.. Functional derivatives of 5,6‐dimethylbenz[c]acridine

Publisher Website
Google Scholar
Abstract
5,5‐Dimethyl‐5,6‐dihydrobenz[c]acridone has been synthesized by three different routes: a, from a condensation of anthranilic acid with 4,4‐dimethyl‐1‐tetraIone; b, by a catalytic hydrogenation of 2‐(o‐nitrobenzal)‐4,4‐dimethyl‐1‐tetralone oxide followed by an acid catalyzed cleavage of the oxide ring and closure of the nitrogen heterocyclic ring; c, a multi‐step process starting with 7‐carboxy‐5,5‐dimethyl‐5,6‐dihydrobenz[c]acridine. Several new functional derivatives of both 5,5‐dimethyl‐5,6‐dihydrobenz[c]acridine and of 5,6‐dimethylbenz[c]acridine were also produced for biological study by others.