1H- and13C-NMR Spectroscopic Studies of Selected Quassinoids

Abstract
The 13C-NMR spectra of some selected C20 quassinoids have been investigated. Unambiguous assignments were obtained through one-bond and long-range heteronuclear correlation spectroscopy. Some previous assignments have been corrected and ambiguities clarified. The usefulness of one-dimensional, long-range, proton-carbon correlation for the structure elucidation of the highly functionalized picrasan skeleton has been demonstrated. Proton homonuclear spectroscopy (COSY and delayed COSY) was useful for establishing the relative stereochemistry at C-1 and C-12, and several diagnostic, long-range couplings are reported for the first time for the picrasan skeleton.

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