Intracrinology
- 1 October 1993
- journal article
- research article
- Published by Wolters Kluwer Health in Current Opinion in Urology
- Vol. 3 (5) , 381-387
- https://doi.org/10.1097/00042307-199310000-00009
Abstract
The prostate synthesizes androgens from dehydroepiandrosterone and its sulfate and contains all the enzymes required to synthesize dihydrotestosterone from these precursors. About 50% of the androgens that stimulate prostate cancer are produced in the prostate; therefore, besides blocking the testes, combination therapy to block dihydrotestosterone's interaction with androgen receptors is essential.Keywords
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