A short, asymmetric synthesis of (–)-pumiliotoxin C
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 24,p. 1838-1839
- https://doi.org/10.1039/c39930001838
Abstract
An asymmetric synthesis of (–)-pumiliotoxin C is accomplished in nine steps from 4-methoxy-3-(triisopropylsilyl)pyridine.Keywords
This publication has 14 references indexed in Scilit:
- Enantiopure 2,3-dihydro-4-pyridones as synthetic intermediates. Asymmetric syntheses of the quinolizidine alkaloids, (+)-myrtine, (-)-lasubine I, and (+)-subcosine IThe Journal of Organic Chemistry, 1992
- Ruthenium-catalyzed hydration of nitriles and transformation of .delta.-keto nitriles to ene-lactamsThe Journal of Organic Chemistry, 1992
- N-acyldihydropyridones as synthetic intermediates. A short synthesis of (±)-pumiliotoxin C.Tetrahedron Letters, 1991
- Chiral dihydropyridones as synthetic intermediates. Asymmetric synthesis of (+)-elaeokanine A and (+)-elaeokanine CJournal of the American Chemical Society, 1991
- Asymmetric synthesis of 2-alkyl(aryl)-2,3-dihydro-4-pyridones by addition of Grignard reagents to chiral 1-acyl-4-methoxypyridinium saltsThe Journal of Organic Chemistry, 1990
- A highly stereocontrolled, four-step synthesis of (.+-.)-lasubine IIJournal of the American Chemical Society, 1988
- (−)-8-PHENYLMENTHOLOrganic Syntheses, 1987
- Asymmetric synthesis VIII: Biogenetically patterned approach to the chiral total synthesis of (−)-pumiliotoxin-CTetrahedron Letters, 1986
- A method for the regiospecific synthesis of enol triflates by enolate trappingTetrahedron Letters, 1983
- An enantioselective synthesis and the absolute configuration of natural pumiliotoxin‐C. Preliminary communicationHelvetica Chimica Acta, 1977