The Total Synthesis of Hydroxyisochamaecynone and Its Stereochemical Assignment

Abstract
The structure of an acetylenic nor-sesquiterpene, hydroxyisochamaecynone, was determined to be 4α-hydroxy-5βH-13-noreudesm-1-en-11-yn-3-one (Ib) by means of the stereoselective total syntheses of two possible stereoisomers, Ib and 4β-hydroxy-5βH-13-noreudesm-1-en-11-yn-3-one.

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