The Epstein-Barr virus nuclear antigen leader protein associates with hsp72/hsc73
Open Access
- 1 December 1995
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 69 (12) , 8169-8172
- https://doi.org/10.1128/jvi.69.12.8169-8172.1995
Abstract
Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) is important for primary B-lymphocyte growth transformation. We now demonstrate that the W repeat-encoded domain of EBNA-LP significantly associates with proteins of the heat shock protein 70 family (hsp72/hsc73). hsp72/hsc73 may mediate the previously observed interaction between EBNA-LP and the retinoblastoma protein or p53.Keywords
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