Effects of Continuous Arteriovenous Hemofiltration on Cardiopulmonary Abnormalities during Anesthesia for Orthotopic Liver Transplantation

Abstract
Y, predisposing these patients to accumulation of extravascular lung water. The effects of the intraoperatives use of continuous arteriovenous hemofiltration (CAVH) on cardiopulmonary and oxygen transport variables were studied in ten patients during and 24 hours after OLT. CAVH prevented increases in pulmonary shunt fraction while decreasing PEEP and FIO2 requirements. Pulmonary compliance was significantly higher after operation in patients receivingCAVH. Before surgical dissection, hemodynamic effects of CAVH were minimal. Postoperatively, patients having CAVH had lower cardiac filling pressures and more normal systemic vascular resistance than did patients not having CAVH. These data suggest that CAVH may be a useful intraoperative technique for patients with impaired renal function undergoing liver transplantation. Address correspondence to Dr. Tuman, Department of Anesthesiology, Rush Presbyterian-St, Luke's Medical Center, 1753 West Congress Parkway, Chicago, IL 60612. Accepted for publication November 11, 1987. © 1988 International Anesthesia Research Society...

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