Estimating the Ascertainment Probability from the Number of Ascertainments per Proband

1 January 1983

journal article
research article
Published by S. Karger AG in Human Heredity

Vol. 33 (2) , 103-108
https://doi.org/10.1159/000153358

Abstract

Several methods of estimating the ascertainment probability from the distribution of the number of ascertainments per proband have been presented in the literature. Here these methods are compared. The Skellam often gives the best fit, but there are counter examples. The estimate from a Poisson distribution is generally close to the best solution.

Keywords

This publication has 5 references indexed in Scilit:

Surveillance of Down’s Syndrome as a Paradigm of Population Monitoring
Human Heredity, 1975
CONGENITAL ANIRIDIA
1960
Some Applications of the Negative Binomial and Other Contagious Distributions
American Journal of Public Health and the Nations Health, 1959
GENETIC TESTS UNDER INCOMPLETE ASCERTAINMENT
1959
THE NEGATIVE BINOMIAL DISTRIBUTION
Annals of Eugenics, 1941