Studies in detoxication. 83. The aromatization of cyclohexanecarboxylic acid in hens
- 1 September 1960
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 76 (3) , 600-602
- https://doi.org/10.1042/bj0760600
Abstract
Cyclo[carboxy-14CJ Hexanecarboxylic acid has been prepared by the reduction of [carboxy-14C]-benzoic acid. cycloHexanecarboxylic acid is extensively aromatized when administered orally to hens. This was proved by the isolation of benzoyl glucuronide and L(+)-ornithuric acid from the urine. By isotope dilution it is shown that of the 14C administered orally to hens as cyclohexanecarboxylic acid (dose 200-260 mg/kg) about 80% is excreted in 24 hr.; 50-60% of the dose is excreted as benzoyl glucuronide and 10-20% ornithuric acid. About 5% of the cyclohexanecarboxylic acid is excreted unchanged.Keywords
This publication has 4 references indexed in Scilit:
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- Studies in detoxication. 78. Glucuronide and ethereal sulphate formation in hensBiochemical Journal, 1959
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