DNA-Induced Transformation in Drosophila: Genetic Analysis of Transformed Stocks
- 1 February 1971
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (2) , 342-346
- https://doi.org/10.1073/pnas.68.2.342
Abstract
The exosome model of transformation in Drosophila melanogaster proposes that DNA fragments enter the cells of treated individuals and become firmly associated with their homologous chromosome segments, but are never integrated into the linear structure of the chromosome. This paper reports results that validate two central predictions of the model: (a) the introduced genetic information usually maps precisely at the site of the target locus, and (b) the original chromosomal information is still present at that site.Keywords
This publication has 3 references indexed in Scilit:
- DNA-Induced Transformation in Drosophila: Evidence for Transmission without IntegrationProceedings of the National Academy of Sciences, 1970
- DNA-Induced Transformation in Drosophila: Locus-Specificity and the Establishment of Transformed StocksProceedings of the National Academy of Sciences, 1970
- Induction of lethal mutations in Drosophila melanogaster by DNAGenetics Research, 1965