The partial synthesis of ergosta-5,7,22,24(28)-tetraen-3β-ol
- 1 January 1970
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 15,p. 939-940
- https://doi.org/10.1039/c29700000939
Abstract
The Diels–Alder adduct between ergosterol acetate and 4-phenyl-1,2,4-triazolin-3,5-dione can be efficiently re-converted into ergosterol by lithium aluminium hydride reduction; using this reaction as a key step, ergosta-5,7,22,24(28)-tetraen-3β-ol has been synthesised in labelled form and shown to be an efficient precursor of ergosterol in yeast.Keywords
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