Interrater Reliability of the Modified Jadad Quality Scale for Systematic Reviews of Alzheimer’s Disease Drug Trials
Top Cited Papers
- 9 March 2001
- journal article
- review article
- Published by S. Karger AG in Dementia and Geriatric Cognitive Disorders
- Vol. 12 (3) , 232-236
- https://doi.org/10.1159/000051263
Abstract
Drug therapies for Alzheimer’s disease (AD) have been evaluated in clinical trials over the past 2 decades. Systematic reviews of AD drug trials can shed more light on the efficacy of pharmaceutical interventions. The modified Jadad scale can be used to assess the quality of trial reports that are candidates for inclusion in these systematic reviews. The interrater reliability of the modified Jadad scale was examined during such a review. Three blinded reviewers rated the quality of 42 AD drug trial reports: the intraclass correlation coefficient was 0.90. The modified Jadad scale appears to be a useful tool for AD research because of the very good interrater reliability. Also, it is composed of items that are well suited to the specific disease characteristics of AD. Further research should focus on the validity of this instrument.Keywords
This publication has 9 references indexed in Scilit:
- Feverfew as a preventive treatment for migraine: a systematic review.Cephalalgia, 1998
- A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study GroupJAMA, 1997
- A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's DiseaseNew England Journal of Medicine, 1997
- The importance of quality of primary studies in producing unbiased systematic reviewsArchives of internal medicine (1960), 1996
- Assessing the quality of reports of randomized clinical trials: Is blinding necessary?Controlled Clinical Trials, 1996
- Assessing the quality of randomized controlled trials: An annotated bibliography of scales and checklistsControlled Clinical Trials, 1995
- The epidemiologist's responsibilities to research subjects in the occupational settingJournal of Clinical Epidemiology, 1991
- A method for assessing the quality of a randomized control trialControlled Clinical Trials, 1981
- Intraclass correlations: Uses in assessing rater reliability.Psychological Bulletin, 1979