Di- and tri-alkylphosphine adducts of S-donor palladacycles as catalysts in the Suzuki coupling of aryl chlorides

Abstract
The reaction of tricyclohexylphosphine with the S-based palladacycle [{Pd(μ-OAc)(κ2-S,C-C6H4CH2SMe)}2] gives several products, regardless of stoichiometry, one of which, [Pd(κ1-OAc)(η1-C6H4CH2SMe)(PCy3)2], has been characterised crystallographically. Despite this, catalysts formed in situ from di- and tri-alkylphosphines and [{Pd(μ-OAc)(κ2-S,C-C6H4CH2SMe)}2] show excellent activity in the Suzuki coupling of a range of deactivated, non-activated and activated aryl chloride substrates.

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