Delineation of AbrB-binding sites on the Bacillus subtilis spo0H, kinB, ftsAZ, and pbpE promoters and use of a derived homology to identify a previously unsuspected binding site in the bsuB1 methylase promote
Open Access
- 1 December 1995
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 177 (23) , 6999-7002
- https://doi.org/10.1128/jb.177.23.6999-7002.1995
Abstract
DNase I footprinting experiments showed that AbrB binds to the regulatory regions of the spo0H, kinB, ftsAZ, and pbpE genes. A conserved motif was found in these and other AbrB-binding sites. A search for Bacillus subtilis DNA sequences containing this motif led to the prediction that AbrB would bind to the promoter controlling the bsuB1 methylase gene. DNase I footprinting experiments confirmed this prediction.Keywords
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