The Ultra-Violet Spectrophotometric Assay of Alkaloids; Part II. Quinine and Strychnine

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Abstract
Summary and Conclusions: A simple ultra-violet spectrophotometric method for assay of mixed solutions of strychnine and quinine has been developed. Strychnine in solutions containing strychnine and quinine down to the ratio of 1:250 could be estimated within 1 per cent, of the actual quantity present. For ultra-violet spectrophotometric assay of strychnine and quinine it is imperative that the mixture should have little or no fluorescence under an ordinary ultra-violet lamp. For assay of the alkaloids in pharmaceutical preparations containing other ingredients, the bases are extracted and estimated as hydrochlorides. The accuracy of the method is largely dependent on the efficiency of such extractions.

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