ORGANOCHLORINE COMPOUNDS IN HUMAN-BLOOD PLASMA AND MILK

  • 1 January 1977
    • journal article
    • review article
    • Vol. 10  (4) , 121-129
Abstract
Organochlorine insecticides and polychlorinated biphenyls (PCB) were assessed in human blood plasma and milk collected from Israeli mothers 2-4 days after childbirth during 1975. The concentration of total DDT (.SIGMA.DDT) was similar in whole plasma and milk (74 ppb vs. 72 ppb) and higher in plasma-extracted lipids than in milk-extracted lipids: 15.12 ppm vs. 5.77 ppm. Levels of .gamma.-BHC, dieldrin and heptachlor epoxide were higher in whole plasma and plasma-extracted lipids than in whole milk or in milk-extracted lipids. PCB had similar concentrations in extracted lipids of plasma and milk but were significantly higher in whole milk than in whole plasma. Higher percentages of organochlorine insecticides and PCB were excreted in milk from mothers between 20-29 than between 30-39, although the younger group had lower levels of these compounds in plasma. Overweight women excreted lower quantities of organochlorine insecticides and PCB than did women of normal weight. [Danger to breast-fed babies resulting from xenobiotic accumulation is a consideration.].

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