The Transformation of Deoxycholic Acid into Allodeoxycholic Acid in the Rat. Bile Acids and Steroids. 174.
- 1 January 1967
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 21 (1) , 87-92
- https://doi.org/10.3891/acta.chem.scand.21-0087
Abstract
Deoxycholic acid was shown to be transformed into allodeoxycholic acid during the enterohepatic circulation of bile in the rat. After intracecal administration of 3[beta]-H3-24-C14-deoxycholic acid, the deoxycholic acid as well as the allodeoxycholic acid isolated from bile and feces had lost most of the tritium label. It is suggested that in the intact rat deoxycholic acid is rapidly equilibrated with 12[alpha]-hydroxy-3-keto-5[beta]-cholanoic acid.This publication has 1 reference indexed in Scilit: