Effect of Acute Reduction in Cardiac Output on the Denervated Kidney

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Abstract
Acute reduction of cardiac output by compression of the pulmonary artery produces equivalent effects in the normal and denervated kidneys on renal blood flow, glomerular filtration rate and Na excretion in the anesthetized dog. Computation of afferent, efferent and postarteriolar resistances also failed to reveal any significant difference between the exptl. and control kidneys. Therefore, it appears that the renal nerves do not participate in the regulation of renal hemodynamics when the cardiac output is acutely reduced.