Paul-Bunnell Antigen in Malignancies and Rheumatoid Arthritis
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 60 (1) , 115-119
- https://doi.org/10.1159/000232331
Abstract
By means of agglutination inhibition test, Paul-Bunnell (P-B) antigen was demonstrated in sera of patients with cancer (5%), lymphomas or leukemias (12.5%) and rheumatoid arthritis (RA) (1.4%) as well as in synovial fluids from RA patients (27%). In contrast, none of 124 normal human sera gave positive results. P-B antigen was also demonstrated in 3 of 12 perchloric acid extracts of cancer tissues and 2 of 11 saline extracts obtained at 100°C from spleens of lymphoma-leukemia patients. Extracts of apparently normal tissues from 16 individuals gave negative results.Keywords
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