Differential effects of ABT-510 and a CD36-binding peptide derived from the type 1 repeats of thrombospondin-1 on fatty acid uptake, nitric oxide signaling, and caspase activation in vascular cells
- 1 November 2007
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 75 (4) , 875-882
- https://doi.org/10.1016/j.bcp.2007.10.025
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signalingBlood, 2008
- Thrombospondin-1 Inhibits Nitric Oxide Signaling via CD36 by Inhibiting Myristic Acid UptakeJournal of Biological Chemistry, 2007
- Thrombospondin-1 Peptide ABT-510 Combined with Valproic Acid Is an Effective Antiangiogenesis Strategy in NeuroblastomaCancer Research, 2007
- Cooperative Activity of Cytotoxic Chemotherapy with Antiangiogenic Thrombospondin-I Peptides, ABT-526 in Pet Dogs with Relapsed LymphomaClinical Cancer Research, 2006
- Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide–mediated vascular smooth muscle relaxationBlood, 2006
- Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathwayThe International Journal of Biochemistry & Cell Biology, 2006
- Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: A safe combinationEuropean Journal Of Cancer, 2006
- Metronomic Low-Dose Chemotherapy Boosts CD95-Dependent Antiangiogenic Effect of the Thrombospondin Peptide ABT-510: A Complementation Antiangiogenic StrategyClinical Cancer Research, 2005
- Thrombospondin-1 Mimetic Peptide Inhibitors of Angiogenesis and Tumor Growth: Design, Synthesis, and Optimization of Pharmacokinetics and Biological ActivitiesJournal of Medicinal Chemistry, 2005
- Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesisCancer Cell, 2005