Increased frequency of DR2 in patients with aplastic anaemia and increased DR sharing in their parents
- 1 May 1986
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 63 (1) , 51-57
- https://doi.org/10.1111/j.1365-2141.1986.tb07494.x
Abstract
68 patients with aplastic anaemia, their parents and healthy siblings were typed for HLA-A, B and DR antigens. Among the patients there is an overrepresentation of DR2. The parents of affected children show an increased compatibility at the DR locus. This situation could favour the expression of recessive gene(s) involved in haematopoiesis and located in the HLA locus.This publication has 18 references indexed in Scilit:
- Evidence for HLA-linked susceptibility factors in childhood leukemiaHuman Immunology, 1983
- HLA associations in Italian and non‐Italian Caucasoid aplastic anaemia patients*Tissue Antigens, 1983
- Antithymocyte Globulin Treatment in Patients with Aplastic AnemiaNew England Journal of Medicine, 1983
- Association of HLA-DRw2 with autoimmune thrombocytopenic purpura.Journal of Clinical Investigation, 1979
- B-Lymphocyte Alloantigens Associated with Systemic Lupus ErythematosusNew England Journal of Medicine, 1978
- STRONG ASSOCIATION BETWEEN HLA-DRW2 AND ANTIBODY-MEDIATED GOODPASTURE'S SYNDROMEThe Lancet, 1978
- HLA ANTIGENS AND HAPLOTYPES IN 200 PATIENTS WITH APLASTIC ANEMIATransplantation, 1976
- APLASTIC ANÆMIA: EVIDENCE FOR AN IMMUNOLOGICAL MECHANISMThe Lancet, 1976
- HL‐A Antigens and Disease Statistical and Genetical ConsiderationsTissue Antigens, 1974
- ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASEAnnals of Human Genetics, 1955