The Involvement of P‐Glycoprotein in Berberine Absorption
Open Access
- 24 October 2002
- journal article
- research article
- Published by Wiley in Basic & Clinical Pharmacology & Toxicology
- Vol. 91 (4) , 193-197
- https://doi.org/10.1034/j.1600-0773.2002.t01-1-910403.x
Abstract
Berberine is an important ingredient in a number of traditional Chinese medicines but has been shown to have poor bioavailability in the dog. The aim of this study was to use the P‐glycopro...Keywords
This publication has 16 references indexed in Scilit:
- Effects of Berberine on Arylamine N-acetyltransferase Activity and 2-Aminofluorene-DNA Adduct Formation in Human Leukemia CellsThe American Journal of Chinese Medicine, 2000
- The Antihypertensive Effect of the Berberine Derivative 6-Protoberberine in Spontaneously Hypertensive RatsPharmacology, 1999
- Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug deliveryJournal of Controlled Release, 1999
- Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to PaclitaxelBritish Journal of Cancer, 1999
- Secretion of Sparfloxacin from the Human Intestinal Caco-2 Cell Line Is Altered by P-Glycoprotein InhibitorsAntimicrobial Agents and Chemotherapy, 1998
- THE PHARMACOLOGICAL ROLE OF P-GLYCOPROTEIN IN THE INTESTINAL EPITHELIUMPharmacological Research, 1998
- Effects of Pluronic Block Copolymers on Drug Absorption in Caco-2 Cell MonolayersPharmaceutical Research, 1998
- Intestinal secretion of drugs. The role of P-glycoprotein and related drug efflux systems in limiting oral drug absorptionAdvanced Drug Delivery Reviews, 1997
- Possible Involvement of Multiple P-Glycoprotein-Mediated Efflux Systems in the Transport of Verapamil and Other Organic Cations Across Rat IntestinePharmaceutical Research, 1995
- Modulation of ATP and drug binding by monoclonal antibodies against P‐glycoproteinJournal of Cellular Physiology, 1991