O-aryl S-methyl phosphorochloridothioates: terminal phosphorylating agents in the phosphotriester approach to oligonucleotide synthesis
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 23,p. 1050-1052
- https://doi.org/10.1039/c39780001050
Abstract
O-Aryl S-methyl phosphorothioates (e.g., 6), prepared by the action of O-aryl S-methyl phosphorochloridothioates (e.g., 4c) on alcohols may be converted into the corresponding phosphate esters (e.g., 7b) by treatment first with 4-nitrobenzaldoximate ion and then with iodine in aqueous pyridine.This publication has 0 references indexed in Scilit: