Focal epithelial hyperplasia in a group of South Africans: Its clinical and microscopic features

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Abstract
Thirty-seven cases of focal epithelial hyperplasia were discovered among pupils of reform schools and none among pupils of ordinary schools. This difference in occurrence was significant (P less than 0.01). Lesions were either discrete papules or clusters of papules; and the lining mucosa was the most affected part. Eighteen cases were examined microscopically revealing the typical features of the condition. The fact that these lesions occurred in a select group of pupils all of whom are classified as Cape Coloured points to either a selective distribution of the disease or a spread of the disease among people living in communal circumstances. This pattern of distribution coupled with the clinical and histological features would fit a disease of viral origin which is also communicable.

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