Progeria Infantum (Hutchinson–Gilford Syndrome) Associated with Scleroderma‐Like Lesions and Acro‐Osteolysis: A Case Report and Brief Review of the Literature

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Abstract
Progeria infantum (Hutchinson–Gilford syndrome) is a very rare syndrome of premature aging characterized by growth retardation and specific, progressive, premature senescent changes of the skin and other tissues. We report a 1.5-year-old girl with loss of scalp hair, eyebrows, and lashes, prominent scalp veins, micrognathia, abnormal ears, loss of subcutaneous tissue, and scleroderma-like areas over the trunk. Radiographic studies revealed coxa valga and acro-osteolysis of the terminal phalanges. The clinical and radiologic features corresponded well with progeria infantum.