Analysis of Analgesic Tablets by Quantitative High-Performance Reversed Phase TLC
- 19 December 1985
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 8 (16) , 2961-2967
- https://doi.org/10.1080/01483918508076612
Abstract
Aspirin, phenacetin, and caffeine in two commercial analgesic tablets were determined by scanning of fluorescence-quenched zones after separation on high performance TLC plates. Assays for the components ranged from 100 to 88% of label values, and agreement between duplicate samples was better than 5%. Use of phenacetin as an internal standard for determination of aspirin and caffeine was not advantageous. The analysis serves well as an introduction to quantitative TLC in undergraduate laboratory courses.This publication has 1 reference indexed in Scilit:
- High performance thin layer chromatographyJournal of Chemical Education, 1984