DEPENDENCE OF GASTROINTESTINAL TUMORS ON GASTROINTESTINAL HORMONES - PENTAGASTRIN STIMULATES GROWTH OF TRANSPLANTED COLON ADENOCARCINOMA IN MICE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 33  (8) , 259-261
Abstract
Gastrin was administered several times to mice with transplantable hepatoma, sarcomas, colon adenocarcinoma and adenocarcinoma of small intestine. Injections of gastrin stimulated the growth of colon adenocarcinoma in mice, but not of the other tumors tested. Dependence upon gastrointestinal hormones of spontaneous carcinogenesis in the gastrointestinal tract and the growth of many gastrointestinal pancreatic and liver tumors is suggested. This hormone dependence could be used for the treatment and prophylaxis of some tumors of the gastrointestinal tract.

This publication has 0 references indexed in Scilit: