Abstract
It usually takes several years to establish a new method in any field of medicine. This has been especially true of the introduction of new anesthetic agents and methods and of intravenous anesthesia in particular. The attitudes of different members of the medical profession to the introduction of new methods of anesthesia have often been diametrically opposite; the skepticism of some has been overbalanced by the unbounded enthusiasm of others. These widely divergent attitudes have not always worked to the best interest of the new method or agent. The history of the evolution of intravenous anesthetic agents amply bears this out.1 In the case of intravenous anesthesia the skepticism on the part of many surgeons and anesthetists was not entirely without justification. For fifty years anesthetic agents had been introduced for intravenous administration, and only a few of them had produced uniformly safe and desirable anesthesia. Therefore, when pentothal

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