Gm Allotyping to Determine the Origin of the Anti‐D Causing Hemolytic Anemia in a Kidney Transplant Recipient

Abstract
Anti‐D causing mild hemolytic anemia was found in the serum and on the red cells of a D‐positive patient who had received a kidney transplant from his D‐negative mother. Anti‐D had been detected in the donor's serum before transplantation. Gm allotyping of the patient's serum, donor's serum, donor's anti‐D, and the unex pected anti‐D in the posttransplantation serum showed the antibody to be of maternal origin. The patient was Gm(fb), the donor Gm(agfb), the maternal anti‐D Gm (afb), and the anti‐D in the posttransplantation serum was Gm(a).