Bile Acid Composition of Some Lizards from Southwestern United States

Abstract
Nine species of lizards [Sceloporus magister, S. occidentalis, S. graciosus, Uta stansburiana, Dipsosaurus dorsalis, Urosaurus graciosus, Phrynosoma platyrhinos, Cnemidophorus tigris, Coleonyx variegatus] representing 3 families were used to investigate bile acid composition of the bile acid pool isolated from gallbladders. Members of the 3 families [Gekkonidae, Iguanidae, Teiidae] contained AC, CA, CDCA, DOCA and LCA [allocholic acid, cholic acid, chenodeoxycholic acid, deoxycholic acid and lithocholic acid, respectively] in varying proportions, Gekkonids and tends, represented by a single species each, had quite similar bile acid spectra, with CA as the primary bile acid. This is surprising since these families have different geographic origins and are only distantly phylogenetically related. In contrast, the 7 species of iguanids had AC as the primary bile acid. At both generic and species levels, the iguanids studied had quite similar bile acid spectra. Within this group, food habits or ecologic distribution appeared to have little effect on the proportion of bile acids.

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