Pyrophosphorolysis-Activated Polymerization (PAP): Application to Allele-Specific Amplification
Open Access
- 1 November 2000
- journal article
- research article
- Published by Taylor & Francis in BioTechniques
- Vol. 29 (5) , 1072-1083
- https://doi.org/10.2144/00295rr03
Abstract
To measure mutation load or to detect minimal residual disease, a robust method for identifying one mutant allele in the range of 106–109 wild-type alleles would be advantageous. Herein, we present...Keywords
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