Grating Acuity at Different Luminances in Wild-Type Mice and in Mice Lacking Rod or Cone Function

Abstract
Purpose. The mouse eye has become an important model in vision research. However, it is not known how visual acuity changes with luminance. Therefore, grating acuity of mice was measured at different luminances in an automated optomotor paradigm. Furthermore, mutant mice lacking either rods (RHO−/− and CNGB1−/−) or cones (CNGA3−/−), or both, were studied to determine the rod and cone contribution to visual acuity.

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